ongoing trial
[대역어] None
[용어속성] Term
[용어속성] Term
The failure of drug repurposing for COVID-19 as an effect of excessive hypothesis testing and weak mechanistic evidence
Article
Published on
Journal: History and philosophy of the life sciences
[Category] COVID19(2023년), SARS, 신약개발,
Journal: History and philosophy of the life sciences
[Category] COVID19(2023년), SARS, 신약개발,
[키워드] agency
Analysis
applied
approval
clinical trial
Compound
conducted
COVID
COVID-19
EBM+
effective
Efficacy
Evidence
example
Excessive hypothesis testing
explain
false-positive result
False-positive results
favor
Hydroxychloroquine
Hypothesis
less
Mechanistic evidence
Medical nihilism.
Medicine
ongoing trial
other diseases
Perspective
risk
second
tested
therapeutic
therapy
Treatment
treatment for COVID-19
Trial
[DOI] 10.1007/s40656-022-00532-9 PMC 바로가기
[DOI] 10.1007/s40656-022-00532-9 PMC 바로가기
Efficacy of COVID-HIGIV in animal models of SARS-CoV-2 infection
Article
[키워드] acute respiratory syndrome
animal model
anti-SARS-CoV-2
baseline
Body weight loss
caused
China
controls
convalescent plasma
coronavirus
COVID-19
COVID-19 vaccines
deaths
Efficacy
evaluated
faster
hamster
hamsters
Hospitalization
Human
Immunoglobulin
intravenous
Lung inflammation
Lung pathology
Lungs
mice
monoclonal antibody
mouse model
ongoing trial
PBS
plasma
reduced
SARS-CoV-2
SARS-COV-2 infection
significantly
Spread
Support
therapeutic option
treated
Treatment
Viral load
virus
was reduced
worldwide pandemic
[DOI] 10.1038/s41598-022-21223-2 PMC 바로가기
[DOI] 10.1038/s41598-022-21223-2 PMC 바로가기
Ivermectin for preventing and treating COVID-19
COVID-19 예방 및 치료를 위한 이버멕틴
Review
Published on
Journal: The Cochrane database of systematic reviews
[Category] COVID19(2023년), SARS, 임상,
Journal: The Cochrane database of systematic reviews
[Category] COVID19(2023년), SARS, 임상,
[키워드] 95% CI
95% confidence interval
acute respiratory syndrome
acute respiratory syndrome coronavirus
acute respiratory syndrome coronavirus 2
addition
Admission
adverse event
adverse events
all-cause mortality
antiparasitic
Antiviral
approach
ARMS
Asymptomatic
certainty
certainty of evidence
citation
classification
Clinical improvement
clinical trial
Cochrane COVID-19 Study Register
coronavirus
coronavirus disease
COVID-19
COVID-19 diagnosis
COVID-19 symptoms
COVID-19 treatment
Data collection
database
death
discharged
disease
disease severity
double-blind
duration of symptom
early stage
early stages
Efficacy
Efficacy and safety
eligible
Evidence
excluded
for inclusion
GRADE
hospital
identify
in vitro
include
increase
index
Infection
infection with SARS-CoV-2
inhibit
inhibitory effect
initial symptom
Inpatient
Inpatients
Intervention
Invasive mechanical ventilation
investigated
Ivermectin
life
mean difference
Mental
Meta-analysis
Mild
Moderate COVID-19
moderate-to-severe COVID-19
molecular hypothesis
Mortality
no effect
non-randomized
ongoing trial
ongoing trials
Open-label
outcome
Outpatient
outpatients
participant
Participants
people with COVID-19
physical
Placebo
placebo-controlled
Postexposure Prophylaxis
Prevent
Quality of life
question
Randomized controlled trial
Randomized controlled trials
RCT
RCTs
receiving
reduce
Registered
Replication
Reporting
request
Research
resolved
risk
Risk of bias
risk ratio
RoB 2
SARS-CoV-2
SARS-COV-2 infection
Science Citation Index
searched
Selection
Serious Adverse Event
Serious Adverse Events
Seven
severe acute respiratory syndrome Coronavirus
Standard of care
treat
treated
treating COVID-19
Treatment
Trial
trials
viral clearance
virus
Web of Science
WHO
WHO guideline
worsening
[DOI] 10.1002/14651858.CD015017.pub3 PMC 바로가기 [Article Type] Review
[DOI] 10.1002/14651858.CD015017.pub3 PMC 바로가기 [Article Type] Review
The use of telecommunication and virtualization among ongoing and discontinued COVID-19 clinical trials: A cross-sectional analysis
진행 중이거나 중단된 COVID-19 임상 시험 중 통신 및 가상화 사용: 단면 분석
Article
[키워드] Chi-square
chi-square tests
clinical
Clinical research
clinical trial
clinical trials
ClinicalTrials
coded
COVID-19
COVID-19 pandemic
cross-sectional analysis
Data collection
Developing
Enrollment
follow-up visits
impacted
Intervention
Kruskal-Wallis test
Kruskal-Wallis tests
limit
lockdowns
measure
MONITOR
ongoing trial
ongoing trials
Other
outcome measures
pandemic
performed
recruitment
Registered
remote
Remote Data Collection
reported
Research
returned
Safe
social distancing
statistically significant difference
Support
telecommunication
Telemedicine
treatments for COVID-19
Trial
trials
variant
Virtualization
Virtualization.
were used
[DOI] 10.1016/j.cct.2022.106681 PMC 바로가기 [Article Type] Article
[DOI] 10.1016/j.cct.2022.106681 PMC 바로가기 [Article Type] Article
Association between smoking, e-cigarette use and severe COVID-19: a cohort study
Original Article
[키워드] adjusted
adjusted hazard ratio
Admission
association
body mass index
Cohort
cohort study
confidence interval
confounding variable
COVID-19
COVID-19 hospitalization
Cox proportional hazard
current
death
demographic factor
disease
E-cigarettes
England
Epidemic
Factor
finding
First wave
Former smoker
higher risk
hospital
Hospitalization
HRs
ICU
ICU admission
intensive care
lower risk
medical records
Mortality
ongoing trial
outcome
Practitioner
PROTECT
protective mechanism
recorded
reduced risk
reduction in
remained
respiratory infections
Result
risk factor
SARS-CoV-2
SARS-COV-2 infection
severe COVID-19
Smokers
smoking
smoking status
Support
the SARS-CoV-2
treat
were assessed
with COVID-19
[DOI] 10.1093/ije/dyac028 PMC 바로가기 [Article Type] Original Article
[DOI] 10.1093/ije/dyac028 PMC 바로가기 [Article Type] Original Article
HPV-associated oropharyngeal cancer: epidemiology, molecular biology and clinical management
Reviews
[키워드] addition
Cancer
Care
Cell
Clinical course
Clinical management
diagnostic biomarker
disease
effort
Epidemiology
greater
highlight
Human
identify
Immunotherapy
IMPROVE
incidence
individuals
lack
molecular basis
Molecular biology
ongoing trial
Oropharyngeal
outcomes
Patient
Precision
Prevalence
Prognosis
Quality of life
review
survival
Symptom
targeted therapy
Treatment
[DOI] 10.1038/s41571-022-00603-7 [Article Type] Reviews
[DOI] 10.1038/s41571-022-00603-7 [Article Type] Reviews
Melatonin, Zinc, and Vitamin C: Potential Adjuvant Treatment for COVID-19 Patients
Nutrition
[키워드] adjuvant
appear
approach
clinical trial
COVID-19
database
duration of symptom
Evidence
hyperinflammation
immune system
IMPROVE
Inconclusive
Intervention
investigated
mechanical ventilation
melatonin
mortality rate
observational study
ongoing trial
outcome
oxygen support
Patient
patients with COVID-19
Potential
Randomized controlled trial
RCTs
reduce
regulate
Research
SARS-CoV-2
searched
small sample size
therapy
Treatment
Trial
trials
Vitamin
Vitamin C
Zinc
zinc supplementation
[DOI] 10.3389/fnut.2021.821824 PMC 바로가기 [Article Type] Nutrition
[DOI] 10.3389/fnut.2021.821824 PMC 바로가기 [Article Type] Nutrition
Association between convalescent plasma treatment and mortality in COVID-19: a collaborative systematic review and meta-analysis of randomized clinical trials
COVID-19에서의 회복기 혈장 치료와 사망률 사이의 연관성 : 무작위 임상 시험의 협력 체계적인 검토 및 메타 분석
Meta-Analysis
[키워드] all-cause mortality
benefit
breath
chance
clinical
clinical trial registry
clinical trials
control patients
convalescent plasma
convalescent plasma treatment
COVID-19
COVID-19 patients
database
did not reduce
died
email
enrolled
Evidence
heterogeneity
hospitalized patient
intensive care
investigated
investigator
investigators
Meta-analysis
Mortality
mortality data
ongoing trial
open
Open Science Framework
Patient
Patient care
patients
patients with COVID-19
Placebo
plasma
provided
random effect
randomized clinical trial
randomized clinical trials
randomized trials
RECOVERY trial
Registered
registry
Result
risk
risk ratio
SARS-CoV-2
searched
supplementary material
systematic review
treat
Treatment
Trial
trials
weight
WHO
WHO International Clinical Trials Registry Platform
[DOI] 10.1186/s12879-021-06829-7 PMC 바로가기 [Article Type] Meta-Analysis
[DOI] 10.1186/s12879-021-06829-7 PMC 바로가기 [Article Type] Meta-Analysis
COVID-19 Advanced Care
Review
[키워드] 28-day mortality
acute respiratory syndrome
Antibiotics
Anticoagulant
anticoagulation
Antiviral agents
antiviral therapies
Care
caused
complications
coronavirus
coronavirus disease
COVID-19
Dexamethasone
Disease progression
Efficacy
Evidence
Hospitalization
hyperimmune
hypoxic respiratory failure
immune
include
increase in
individuals with COVID-19
management
monoclonal antibodies
monoclonal antibody
multiorgan disease
ongoing trial
outcome
pandemic
passive immune therapies
Patient
Pneumonia
public health
reduce
requiring supplemental oxygen
Research
SARS-CoV-2
Severe acute respiratory syndrome
systemic corticosteroids
therapy
usual care
[DOI] 10.3390/jpm11111082 PMC 바로가기 [Article Type] Review
[DOI] 10.3390/jpm11111082 PMC 바로가기 [Article Type] Review